Helicobacter pylori-negative Peptic Ulcer / 胃肠病学

ABSTRACT

With the decrease of Helicobacter pylori (Hp) infection, the proportion of Hp-negative peptic ulcer tends to increase. Hp-negative peptic ulcer has a high rate of bleeding and ulcer recurrence, with difficulty in diagnosis and treatment. This article reviewed the diagnosis, clinical characteristics and pathophysiology of Hp-negative peptic ulcer.